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KMID : 1024520110200081031
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Journal of the Environmental Sciences
2011 Volume.20 No. 8 p.1031 ~ p.1039
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Influences of Chitosan, Sericin and Collagen Extract Complexes on the Improvement Actions of Lipid Component in Diabetes
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Kim Han-Soo
Jang Seong-Ho
Yoon Myung-Joo
Choi Woo-Seok
Kang Jin-Soon
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Abstract
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This study was conducted to examine the influences of chitosan, sericin and collagen extract complexes (1:1:1, w/w/w, CSC-F-005) in blood glucose and lipid concentrations in the sera of streptozotocin (STZ, 55 mg/kg BW, IP injection)-induced diabetic rats (SD strain) fed on experimental diets for 5 weeks. The concentrations of blood glucose, total cholesterol, HDL-cholesterol, ratio of HDL-cholesterol concentration to total cholesterol, atherosclerotic index, LDL-cholesterol, free cholesterol, cholesteryl ester, triglyceride (TG) and phospholipid (PL) in serum were effective on the metabolic regulation in diabetic rats. The activities of alkaline phosphatase (ALP) and aminotransferase (AST, ALT) in
serum were lower in the extract complexes (CSC-F-005) than in the diabetic rats. The results shown above suggested that CSC-F-005 extract complexes supplementation effectively improvement of blood glucose and lipid components in the serum of STZ-induced diabetic rats.
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KEYWORD
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Chitosan, Sericin, Collagen, Extract complexes, Diabetes, Blood glucose, Lipid component
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